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Consumption with natural health products (e.g. bitter orange extract, synephrine, octopamine, ephedra) which increase blood pressure, or other caffeine containing products (e.g. medications, coffee, tea, colas, guarana, mate) is not recommended. \nConsult a health practitioner prior to use if you are of child bearing age, have cardiovascular disease or hypertension, diabetes, prostate disorders, or are taking prescription medications. 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